Following an accident, Danielle "Dani" Moonstar (Blu Hunt) awakes at a medical facility to discover she's handcuffed to a gurney. Dr. Cecilia Reyes (Alice Braga) explains that she survived her ordeal thanks to her abilities as a mutant.
She is being treated along with Scottish teen Rahne Sinclair (Maisie Williams), Kentucky's Sam Guthrie (Charlie Heaton), Brazilian pretty boy Roberto De Costa (Henry Zaga), and Russian brat Illyana Rasputin (Anya Taylor-Joy), who each describe their first experiences with their powers.
As Dani’s powers are still unknown, Dr. Reyes often keeps her under observation and runs tests on her. The teen mutants try to get along, but there are disruptions and fights among them.
It soon becomes apparent that this facility is a prison for the troubled youths and that Dr. Reyes has ulterior and sinister motives for their treatments. Each of the mutants have their own demons from their past and soon their nightmares start turning into reality. These new mutants must band together and face their past sins in order to escape this house of horrors.
Hiding from the Empire's fleet of Imperial Star Destroyers, the Rebellion takes refuge on the ice planet of Hoth. While out on patrol, Luke Skywalker (Hamill) is confronted by the spirit of Obi-Wan Kenobi (Guinness), who instructs him to go to Dagobah and seek out the Jedi Master Yoda (Oz). The rebels are discovered, and following a battle with the Empire, Luke leaves the Rebellion to find Yoda, while Princess Leia (Fisher), Han Solo (Ford), Chewbacca (Mayhew) and the droids C-3PO (Daniels) and R2-D2 (Baker) leave Hoth in the Millennium Falcon.
After arriving on Dagobah, Luke begins his training with Yoda to becoming a Jedi Knight. Meanwhile, Darth Vader (Prowse/Jones), dispatches a number of bounty hunters to seek out Princess Leia and her protectors. Boba Fett, one of the hunters, tracks the Millennium Falcon to Cloud City where he devises a trap.
When Harry Potter and his best friends, Ron Weasley and Hermione Granger, return to Hogwarts School of Witchcraft and Wizardry for their sixth year of magical education, they're unhappy to learn that Severus Snape has been promoted to Defence Against the Dark Arts instructor, while Horace Slughorn has been convinced after much persuasion on Dumbledore's part to take Snape's place as Potions teacher.
Dumbledore needs Harry to help him uncover a memory that exists within Professor Slughorn. They need to see it if they are to successfully fight Lord Voldemort's dark forces. Meanwhile, Harry becomes the top student in his potions class, due to the extra instructions written in ink in his text book by someone who identifies himself only as "The Half-Blood Prince."
Dumbledore takes Harry on an expedition to find a magical object called a Horcrux and destroy it after they find out that Voldemort has separated his soul into seven pieces and hidden them within these objects. If they can find all the pieces of Voldemort's soul and destroy them, they'll be able to defeat the dark lord and save the wizarding world.